To Eat 1. Frost Diner Warrenton, Virginia Rumored to be America's oldest continuously running diner. 540-347-3047
2. Big Texan Steak Ranch Amarillo, Texas If you can finish off a 72-ounce steak, it's free. bigtexan.com
3. In 'N' Out Burger California, Arizona, and Nevada Order from the not-so-secret menu. in-n-out.com/secretmenu.asp
4. Dutch Haven Ronks, Pennsylvania Sample shoofly pie at the windmill-topped kitchen that made it famous. dutchhaven.com
5. Kopp's Frozen Custard Milwaukee Call this Dairy State landmark's hotline (414-961-2006) for the homemade flavor of the day. kopps.com
6. The Mission San Xavier Del Bac Near Tucson Enjoy Indian fry bread and chili in front of this 1797 "white dove of the desert" for just a few bucks. 520-294-2624
7. Tortuga's Lie On North Carolina's Outer Banks One staffer calls it "hands down, the best local surf grill ever." tortugaslie.com
8. The Anchor Grill Covington, Kentucky This 24-hour greasy spoon features a mini jukebox (with dancing Barbies) at every table. 859-431-9498
9. Dante & Luigi's Philadelphia Mangia Old World specialties in the heart of South Philly's Italian Market. danteandluigis.com
10. Rods Grill Warren, Rhode Island Fill up on award-winning $1.45 New York System wieners, topped with meat sauce, chopped raw onions, and celery salt. 401-245-9405
11. The Salt Lick Driftwood, Texas Pig out on heaping helpings of open-pit barbecue. 512-858-4959
12. And for more, read "American Pie: Slices of Life (And Pie) From America's Back Roads" by Pascale Le Draoulec (Harper Paperbacks, $13) or go to dinercity.com for links to historic diners around the country.
To Take a Hike 13. Shenendoah National Park Virginia Includes 101 miles of the Appalachian Trail. 540-999-3500
14. Grand Canyon National Park Arizona Try the South Kaibab trail for fewer crowds. 928-638-7888
15. Harriman State Park New York Hoof it to 31 lakes and reservoirs, three beaches, and two public camping areas. 845-351-2568
16. Great Smoky Mountains National Park Tennessee The most visited national park in the United States, with more than 800 miles of trail. 865-436-1200
17. Acadia National Park Maine Tide pools, granite peaks, and lighthouses. 207-288-3338
18. Rocky Mountain National Park, Colorado Colorado A wonderland for mountaineers and backcountry campers. 970-586-1206
19. Grand Teton National Park Wyoming For spectacular lakes and moose, elk, and bison sightings, try Paintbrush Canyon. 307-739-3300
20. Yosemite National Park California To chase waterfalls. 209-372-0200
21. Glacier National Park Montana See it before the glaciers melt! 406-888-7800
22. Mount Saint Helens Washington For those who really are okay with climbing an active volcano. 360-274-0962
23. Temescal Canyon California Breathtaking views within spitting distance of Los Angeles. 310-455-2465
24. Bryce Canyon National Park Utah Unrivaled rock formations and stargazers' campgrounds at 8,200 feet. 435-834-5322
25. Ketchum, Idaho Wildflower meadows and fly-fishing streams. 866-305-0408
26. Or visit nps.gov for the official directory of National Parks.
To Hear a Good Story 27. For driving across the U.S., pop in an audiobook of "My Antonia" by Willa Cather (Tantor Media, $20)
28. For cruising along I-95: "A Walk In the Woods" by Bill Bryson (Corgi Audio, $31)
29. For late-night drives: "The Ultimate David Sedaris" (Hachette Audio, $100)
30. For long afternoon drives, "Prairie Home Companion 25th Anniversary Collection" by Garrison Keillor (Highbridge Audio, $40)
31. For roadside diner junkies: "Nickled and Dimed" by Barbara Ehrenreich (Recorded Books, $30)
32. For road-tripping in general: "Horatio's Drive: America's First Road Trip" by Dayton Duncan (Random House Audio, $25)
To Sleep In Style 33. Thunderbird Hotel Marfa, Texas A trendy redesign of a classic motor lodge in the arty Texas town. thunderbirdmarfa.com
34. Wigwam Village Motel No. 2 Cave City, Kentucky Snooze in a concrete tepee from a 1950s-era chain. wigwamvillage.com
35. Shack Up Inn Clarksdale, Mississippi Sidle into a renovated sharecropper's shack on a former cotton plantation. 662-624-8329
36. The Hostel X Teton Village, Wyoming Rustic, cozy, and cheap rooms with private baths and amazing views of the Teton Mountains. hostelx.com
37. The Horizon Hotel Palm Springs, California Renovated 1950s-style bungalows with top-notch amenities. thehorizonhotel.com
38. Shady Dell Bisbee, Arizona Park yourself for the night in a vintage Airstream trailer (with period details). theshadydell.com
39. Hotel San Jose Austin, Texas The stylish, cozy Hotel San Jose was the most-nominated destination on this list by Blueprint editors. sanjosehotel.com
40. KOA Campgrounds Around the country, these campgrounds feature gambrel-roofed log "kabins" with porch swings, hibachis, and gingham curtains. koa.com
41. Or peruse "Motel America: A State-By-State Tour Guide To Nostalgic Stopovers" by Andrew Wood and Jenny Wood (Collectors Press, $15).
To Learn a New Language 42. "To Budge" To cut in line (Minnesota, Wisconsin, Iowa)
43. "Toad Choker" A very heavy rain (Texas)
44. "Packy" A liquor store (New England)
45. "Outfit" An automobile (Wyoming)
46. "Rack" One pound of barbecue (the South)
47. "Jimmies" Candy sprinkles (the Northeast)
48. "Bang" To make a left turn (Boston)
49. "Langiappe" Something extra (Louisiana)
To See Natural Wonders (That You May Have Overlooked) 50. Slide Rock State Park Sedona, Arizona Ride the natural water chute at this state park. 928-282-3034
51. Congress Avenue Bats Austin, Texas Watch up to 1.5 million bats take flight at sunset every day. 512-416-5700, ext. 3636
52. Crystal Cave South Bass Island, Ohio Crawl inside one of the world's largest geodes. heinemanswinery.com
53. Barringer Meteor Crater Near Winslow, Arizona Nearly a mile wide and 50,000 years old. barringercrater.com
54. Kelso Dunes Kelso, California 600-foot-tall sand dunes that make booming sounds as they shift. 760-733-4456
55. Everglades National Park Homestead, Florida Marshes, mangroves, and gators make up a subtropical wilderness. 305-242-7700
56. And check out "1,001 Natural Wonders You Must See Before You Die" by Michael Bright (Barron's Educational Series, $35).
To See Unnatural Wonders
57. Prada Marfa Near Valentine, Texas Germany-based artists Michael Elmgreen and Ingmar Dragset's life-size sculpture of a Prada store, on I-90.
58. Crazy Horse Memorial Crazy Horse, South Dakota One man's own personal Rushmore, 60 years in the carving. crazyhorse.org
59. Beer-Can House Houston, Texas Talk about aluminum siding! 713-926-6368
60. The World's Largest Ball of Twine Cawker, Kansas More than 1,400 miles of twine, weighing almost 9 tons. 785-781-4713
61. Hollywood, California Plastic surgery capital of the United States.
62. The Corn Palace Mitchell, South Dakota It gets a new mural-facade (made of corn, naturally) every year. cornpalace.org
63. The World's Largest Termite Providence, Rhode Island At 58 feet long, it perches atop New England Pest Control in Providence. 401-941-5700
64. Al Johnson's Swedish Restaurant Sister Bay, Wisconsin During the summer, goats graze the grass roof of the restaurant. 920-854-2626
69. Route 100 Vermont Verdant green in the summer, snow white in the winter, and a cornucopia of colors in the fall.
70. Hana Highway Maui, Hawaii A twisty trail of waterfalls, beaches, and ocean vistas.
71. Red Rocks Scenic Byway, Route 179 Sedona, Arizona When the sun hits the sandstone just right, there's nothing like it.
72. Seward Highway Alaska Gorgeous glaciers, waterfalls, and wildlife.
73. Skyline Drive/Blue Ridge Parkway Virginia A 105-mile stretch overlooking the Blue Ridge Mountains.
74. Carova Beach North Carolina's Outer Banks Take a four-wheel drive right onto the beach.
75. Consult roadtripusa.com or "Road Trip USA" by Jamie Jensen ($30, Avalon TravelPublishing) to plan itineraries with detailed maps, background information, and attractions.
To Find a Bargain 76. Brimfield Antiques Show Brimfield, Massachusetts The largest outdoor antiques show in New England, July 10 to 15, 2007. brimfield.com
77. All Night Flea Market Wheaton, Illinois 5 p.m. to 4 a.m., August 25. 715-526-9769
78. Deco to Pop atSommerivlle Center Antiques Somerville, New Jersey Shop for vintage modern finds. 908-595-1887
79. Rose Bowl Flea Market Pasadena, California Shop with designers and movie stars the second Sunday of every month. rcgshows.com
80. The Northern California Swap Meet Alameda, California A less-crowded, quality alternative to the Rose Bowl, also on Sundays. 510-769-7266
81. Deseret Industries A fruitful chain of thrift shops in seven Western states. (Locals call it simply "DI.")
To Drink Like a Local 83. Lafitte's Blacksmith Shop New Orleans An ancient, cavernous dive where Tennessee Williams used to tipple. 504-593-9761
84. Double Down Saloon Las Vegas The friendly, off-Strip biker hangout known as the "anti-Vegas" is open 24/7. doubledownsaloon.com
85. Inwood Lounge Dallas Retro cocktails and indie films in an Art Deco movie house. 214-764-9106
86. Tootsies Orchid Lounge Nashville Live country music in a bar with tons of history and character. 615-726-0463
87. Billy Goat Tavern Original Chicago The bar that inspired John Belushi's "Cheezborger, Cheezborger, Cheezborger" skit on "Saturday Night Live." billygoattavern.com
88. The Rhinebeck Cantina and Grille Rhinebeck, New York Great music and a down-to-earth, arty crowd in a 19th-century library. 845-876-6816
89. 500 Club on Guerrero San Francisco Dirt-cheap beer + a great jukebox = the ultimate dive. 415-861-2500
90. Fox's Sherron Inn Miami Virtually unchanged since 1946, with dim lighting, red vinyl booths, and Sinatra on the jukebox. 305-666-2230
91. Citysearch.com provides reliable reviews of bars (and more) in cities and towns all over the country.
To Crank Up the Stereo and Sing Along 92. Rolling Stones, "Sticky Fingers" 93. Beach Boys, "Endless Summer" 94. Bruce Springsteen, "Born to Run" 95. Ray Charles, "Anthology" 96. Madonna, "The Immaculate Collection" 97. Johnny Cash, "The Essential Johnny Cash" 98. Stevie Wonder, "The Definitive Collection" 99. Patsy Cline, "Gold" 100. Download our exclusive road-trip playlist.
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